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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MMEL1
All Species:
16.36
Human Site:
S527
Identified Species:
32.73
UniProt:
Q495T6
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q495T6
NP_258428.2
779
89367
S527
R
R
L
D
E
E
Y
S
N
L
N
F
S
E
D
Chimpanzee
Pan troglodytes
XP_001150860
781
89158
S529
R
R
L
D
E
E
Y
S
N
L
N
F
S
E
D
Rhesus Macaque
Macaca mulatta
XP_001105708
750
85452
E499
K
L
N
N
E
Y
L
E
L
N
Y
K
E
D
E
Dog
Lupus familis
XP_546737
807
92419
S555
K
H
L
D
E
E
Y
S
N
L
N
F
S
E
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLI3
765
88681
S513
K
H
L
D
E
E
Y
S
S
L
T
F
Y
E
D
Rat
Rattus norvegicus
P0C1T0
774
89178
S522
R
H
L
D
E
E
Y
S
S
L
T
F
S
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001233077
749
86047
A497
E
K
L
D
Q
E
Y
A
N
L
N
F
S
E
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_689191
755
86752
A503
K
K
L
D
Q
E
Y
A
H
L
N
F
S
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_511056
849
96515
L600
L
E
Q
E
Y
V
N
L
T
I
V
P
D
N
F
Honey Bee
Apis mellifera
XP_392502
776
89056
L527
L
S
K
E
Y
V
M
L
N
I
T
E
N
H
F
Nematode Worm
Caenorhab. elegans
O16796
848
97043
L597
L
D
K
Q
Y
L
G
L
S
I
S
D
S
D
T
Sea Urchin
Strong. purpuratus
XP_781407
763
86739
L515
L
N
E
E
Y
E
D
L
D
F
R
L
N
D
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.9
50.8
82.6
N.A.
77
77.6
N.A.
N.A.
66.2
N.A.
59.9
N.A.
39
40.5
35
38.1
Protein Similarity:
100
97.1
72
89
N.A.
88.6
88.8
N.A.
N.A.
81.6
N.A.
77.6
N.A.
55.9
59.8
54.1
58.5
P-Site Identity:
100
100
6.6
86.6
N.A.
66.6
80
N.A.
N.A.
66.6
N.A.
60
N.A.
0
6.6
6.6
6.6
P-Site Similarity:
100
100
33.3
93.3
N.A.
80
86.6
N.A.
N.A.
86.6
N.A.
100
N.A.
13.3
26.6
33.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
17
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
59
0
0
9
0
9
0
0
9
9
25
42
% D
% Glu:
9
9
9
25
50
67
0
9
0
0
0
9
9
59
17
% E
% Phe:
0
0
0
0
0
0
0
0
0
9
0
59
0
0
17
% F
% Gly:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% G
% His:
0
25
0
0
0
0
0
0
9
0
0
0
0
9
9
% H
% Ile:
0
0
0
0
0
0
0
0
0
25
0
0
0
0
0
% I
% Lys:
34
17
17
0
0
0
0
0
0
0
0
9
0
0
0
% K
% Leu:
34
9
59
0
0
9
9
34
9
59
0
9
0
0
0
% L
% Met:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
9
9
0
0
9
0
42
9
42
0
17
9
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% P
% Gln:
0
0
9
9
17
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
25
17
0
0
0
0
0
0
0
0
9
0
0
0
0
% R
% Ser:
0
9
0
0
0
0
0
42
25
0
9
0
59
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
9
0
25
0
0
0
9
% T
% Val:
0
0
0
0
0
17
0
0
0
0
9
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
34
9
59
0
0
0
9
0
9
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _